What is Nitric Oxide?

The human body naturally produces a gas called nitric oxide. Its purpose? Nitric oxide, or NO, communicates between cells in the body.

Nitric oxide is produced when enzymes are broken down into an amino acid called L-Arginine. This is precisely why you will find the ingredient L-Arginine instead of the gas nitric oxide on NO supplement labels. L-Arginine is also naturally found in foods like crab, shrimp, sesame seeds, spinach, and turkey.

Whether in supplement form or in the diet, L-Arginine is a building block of nitric oxide that will improve strength, enhance recovery, and even increase muscle mass. The use of a nitric oxide booster can promote better results in a workout program and improve recovery time directly after exercise.

In order to supply the body with the nitric oxide that it needs, the protein amino acid L-Arginine is vital to increase NO production. A nitric oxide supplement will provide cells with L-Arginine to increase oxygen delivery, improve mental focus and concentration, reduce fatigue, and enhance power during a workout.

Throughout the body, the production of nitric oxide from L-Arginine will immediately increase circulation, providing noticeable results for exercisers and bodybuilders alike. Beyond exercise results, regular nitric oxide supplementation can also naturally protect the body against heart attack and stroke, according to researcher and Nobel Prize winner Louis Ignarro.1

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How Does It Work?

Amino acids are popular supplement ingredients and can support healthy muscle growth and development. More specifically, the amino acid L-Arginine is a critical supplement to take to produce nitric oxide to act as a vasodilator in the body.

When taken for the purpose of performance enhancement, L-Arginine will produce nitric oxide to support healthy circulation and adequate oxygen flow throughout the body. In order for muscles to function powerfully and effectively in a workout, oxygen flow and circulation are critical; healthy circulation to and from muscle tissue after a workout will also support speedy recovery.

Taking a Genesis Nutrition nitric oxide supplement works in a simple chain of events:

  1. L-Arginine is absorbed by the body to produce nitric oxide.
  2. Nitric oxide communicates between cells to improve blood flow and circulation.
  3. Increased blood and oxygen circulation contribute to quick nutrient absorption and faster post-workout recovery.

Since nitric oxide works as a vasodilator to quickly boost circulation, improved glucose uptake is an added by-product. Regular weight training can cause muscle tissue breakdown, otherwise known as catabolism. Unless the body receives ample nutrients to trigger recovery, catabolism will continue to destroy healthy muscle tissue.

Nitric oxide plays a pivotal role in reversing this process by supporting circulation and enhancing blood glucose delivery to hungry muscle tissue. Nitric oxide boosters are designed for this specific reason - to counteract muscle catabolism and increase workout recovery time by providing damaged cells and muscle tissue with additional glucose.

What are the benefits of Nitric Oxide?

Nitric oxide is an impressive supplement to take for both health and fitness benefits. The team at Genesis Nutrition Australia has compiled the following list of the many benefits you can receive from taking an NO booster:

  • Increased circulation. As we’ve already covered, nitric oxide immediately improves blood flow to enhance workout results and aid in recovery. But beyond that, a surge in blood flow throughout the body will help to stabilize core temperature during a rigorous workout to maintain energy. Many times, the body will consume energy to regulate temperature as inner heat rises during a hard workout. Increased circulation will make it easier to normalize temperature so that energy can be expended where it counts during exercise.
  • Better endurance. If you want to run faster and train stronger, nitric oxide is the supplement to take. Both strength and endurance athletes can benefit from a nitric oxide booster to quickly supply much-needed oxygen to muscle tissue. This type of immediate oxygen delivery will allow you to exercise for longer without fatigue; adequate oxygen flow is especially beneficial to exercisers at higher altitudes and athletes training for endurance events.
  • Improved strength. Nitric oxide works as a chemical transmitter and communicator in the body to increase strength as a result of resistance training. HealthGuidance.org confirms that nitric oxide can support an extended pump, faster muscle growth and recovery, and increased stamina and strength in a workout. This is attributed to increased blood flow and oxygen transport that quickly delivers nutrients to skeletal muscles.2

While nitric oxide is considered a newer supplement in the health world, it has received support from a number of clinical studies. Most commonly, nitric oxide is used to increase strength through improved blood flow to muscles during exercise. It can also provide the added benefit of strengthening immune function.

Nitric Oxide Supplements: Timing and Dosage

To date, set dosage guidelines for nitric oxide supplements have not yet been established. This is why it is critically important to read product directions carefully before taking a nitric oxide booster.

Nitric oxide supplements are available in powder, liquid, capsule, tablet, or pill form. Since liquid is more readily absorbed by the body, recommended liquid doses of nitric oxide boosters are often less than powder or tablet supplements.

Some manufacturers recommend nitric oxide supplement dosage based on tolerance. To begin, you may be directed to take only one serving per day up to a half hour before exercise. A serving may consist of 1000 mg of L-Arginine, in addition to other active ingredients. After personal tolerance has been evaluated, dosage may increase up to two servings prior to exercise. For the best results, it is recommended to stay hydrated by drinking water throughout your workout.

It’s essential to stick to product directions and avoid overdose of the amino acid L-Arginine. Exceeding the recommended dosage of a nitric oxide supplement may cause diarrhoea, nausea, weakness, or exhaustion. Once again, since clear dosage guidelines have not yet been established for L-Arginine, it’s imperative to start slowly and adjust your dosage as needed based on individual tolerance.

Begin gradually by taking the smallest recommended dose for one week. After assessing your reaction, you can increase your dosage to find the optimal amount for your personal workout program.


1. "Louis J. Ignarro - Autobiography." Nobelprize.org. N.p., n.d. Web. 29 Nov. 2012.
2. Ku-Lea,  Chester. "The Role of Nitric Oxide in Bodybuilding." Health Guidance - Free Health Articles. N.p., n.d. Web. 29 Nov. 2012.

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